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Clinical Trial Details
Pharmacokinetic study of single dose dutasteride in healthy subjects
Clinical Trial ( IRB ) #: 06-217S-2
Title: Pharmacokinetic study of single dose dutasteride in healthy subjects
Principal Investigator: Dr. Jonathan Covault
Description: Alcohol abuse and dependence remain important public health problems. The chemical mechanisms by which alcohol affects the nervous system are not well understood. Recent theories suggest that alcohol stimulates release of "neuroactive" steriod hormones which are important mediators of alcohol effects. This pilot study seeks to identify the most appropriate dosage of an FDA approved medication, dutasteride, which blocks the metabolism of steroid hormones, so that dutasteride can be used as a pharmacologic probe for the biochemistry of alcohol effects in human subjects in a subsequent study.
Classification:
  Addiction/Substance Abuse
Eligibility Criteria: Check with study contact
How to Contact: Michelle Slivinsky. Telephone: (860) 679-2587. Email: Slivinsky@uchc.edu
Enrollment Status/Comments: Not Recruiting.
Comments: Closed to enrollment.